Of course you understand that when high-tech civilizations meet low-tech civilizations,
low-tech always loses badly, even when high-tech isn’t deliberately trying to
exterminate low-tech.
So when the tentacled aliens arrive in their high-tech spacetime warping
vehicles, it will mean very bad things for us, even if we do have
the advantage of opposable thumbs. There’s only one thing that can save
us, even if they arrive with the best of intentions: the first one that
gets off its spaceship, before it can gabble out “znɚʂx pɷʆwrnaʡɮ snȜʑʥϢxx” (“We come in peace! Behold, we bring you gifts of beads,
trinkets, and digital watches!”), we kill it and eat it and hang a few tentacles by our front door in plain view of whatever else is in that high-tech spacetime warping
vehicle.
When word gets back to the home planet, they’ll decide our crap-covered
hornet’s nest of a planet is too disgusting to mess with, when Argelius II
is right next door to us (next door for a galaxy-hopping civilization, anyway)
and has a “Gun-Free Zone” sign prominently posted in the front yard to
boot.
As precedent, I refer you to the Jivaro Indians of Ecuador and Peru.
The Spanish conquistadors utterly destroyed the great civilizations of
the Aztecs and the Incas, but the Jivaro are still there today. Why?
Because they never tried to make nice with the high-tech civilization;
they simply regarded shrunken Spanish heads as delightfully chic
accessories for their mud huts. It wasn’t long before everyone needed a
couple of shrunken Spanish heads hanging on the front door
and the
conquistadors decided to move on to less-hazardous and more-promising
enterprises like searching for the Seven Cities of Gold and the Fountain of Youth.